Device-guided Breathing for Shortness of Breath in COPD

Completed · Not applicable

Conditions studied: COPD, Dyspnea, Hyperinflation

In brief

Although drug therapies and pulmonary rehabilitation have greatly improved COPD symptoms, as many as 50% of patients with severe COPD have inadequately controlled dyspnea. Device-guided breathing is a behavioral intervention that guides respiratory rates into a therapeutic range; prolongation of the expiratory phase improves hyperinflation, the most significant driver of dyspnea in this population. Device-guided breathing, has no known side-effects, and may represent a cost effective adjunctive treatment for dyspnea in severe COPD.

Key facts

Study ID

NCT01286181

Run by

Mayo Clinic

People needed

11

Starts

2011-01-01

Expected to finish

2011-12-01

Last updated by the study team

2013-04-04

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Current or former cigarette smokers of at least 10 pack-years
• Clinically significant dyspnea, as determined by a score of at least 2 on the Medical Research Council Dyspnea Score questionnaire (0-4), or through pulmonary function test results of a residual volume (RV) of > 150% predicted or an FEV1 of <65% predicted
• Clinical diagnosis of chronic obstructive pulmonary disease

You may not qualify if…

• Unable to use the slow-breathing device due to hearing impairment
• Poor motivation or lack of interest in using the device
• Pulmonary Rehabilitation ordered as a new therapy at the time of enrollment

Where it is running

• Mayo Clinic in Rochester — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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