Comparison of Retinol 1.0% and Tretinoin 0.02% in the Treatment of Moderate to Severe Photodamage and Wrinkles

Completed · Phase 2

Conditions studied: Photodamaged Skin, Wrinkles

In brief

The purpose of this study is to assess the comparative efficacy of retinol 1.0% and tretinoin 0.02% in minimizing wrinkles, discoloration, roughness, and other signs of moderate to severe photodamage. Our hypothesis is that both products will be of comparable benefit.

Key facts

Study ID

NCT01283464

Run by

Johns Hopkins University

People needed

24

Starts

2010-11-01

Expected to finish

2011-12-01

Last updated by the study team

2016-04-04

Who can join

Age: 35 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 35 or over
• Moderate to severe photodamage

You may not qualify if…

• History of facial cosmetic surgery, facial resurfacing procedures, deep peels, or facial fillers
• History of keloids or hypertrophic scars
• Use of oral steroids or oral retinoids (such as Accutane) in past 6 months

Where it is running

• Johns Hopkins Dept. of Dermatology — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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