Study to Compare Laser Assisted New Attachment Procedure (LANAP) to Traditional Treatments of Chronic Periodontitis

Completed · Not applicable

Conditions studied: Chronic Periodontitis

In brief

The purpose of this study is to compare the Laser Assisted New Attachment Procedure (LANAP protocol) using the Free-running (FR) Pulsed Neodimium: Yttrium aluminium garnet (Nd:YAG) laser to Scaling and Root Planing (SRP) alone, Modified Widman Flap (MFF) surgery, and Coronal Debridement (CD) alone with respect to periodontal clinical attachment level gain.

Key facts

Study ID

NCT01282229

Run by

Institute for Advanced Laser Dentistry

People needed

59

Starts

2010-10-01

Expected to finish

2014-10-01

Last updated by the study team

2015-10-14

Who can join

Age: 25 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects will have chronic adult periodontitis as characterized by all four quadrants of the mouth.
• Subjects will be 25-75 years of age.
• Subjects will be able to follow verbal and/or written instructions, perform Oral Hygiene according to the protocol, and return to the center for specified study visits.
• Subjects must have had no subgingival scaling instrumentation including scaling and root planing, regular periodontal maintenance procedures or any subgingival cleaning < 12 (twelve) months prior to Baseline examination.
• Subjects must have had no history of periodontal surgical procedures of any type prior to Baseline examination.
• Subjects must be non-smokers of any type or former smokers (>6 (six) months stopped), and not using or taking any nicotine product.
• Subjects will have clinical and/or radiographic evidence of subgingival calculus in each quadrant.
• Subjects have no more than one missing tooth per quadrant, excluding 3rd molars.
• Subjects will be able to sign the informed consent form.

You may not qualify if…

• Subject receiving subgingival scaling instrumentation including scaling and root planing, regular periodontal maintenance procedures or any subgingival cleaning less than twelve (12) months prior to Baseline examination.
• Subjects receiving periodontal surgery of any type prior to Baseline examination.
• Subjects with dental implants.
• Subjects with a compromised heart condition, history of rheumatic fever, or joint replacement requiring prophylaxis.
• Subjects having taken systemic cancer therapy and/or radiation therapy at any time
• Subjects with clinically significant acute or concurrent illness
• Subjects with clinically significant chronic illness.
• Subjects with a disease of the connective tissue.
• Subjects taking medications which are likely to cause gingival hyperplasia, within ONE MONTH prior to Baseline examination
• Subjects taking antimicrobials within ONE MONTH prior to Baseline examination
• Subjects taking non-steroidal anti-inflammatory drugs at a therapeutic dose within the TWO WEEKS prior to Baseline examination.
• Subjects taking steroids of any kind within ONE MONTH prior to baseline examination.
• Subjects taking continuous low doses of tetracycline within THREE MONTHS prior to Baseline examination
• Subjects taking an investigational drug within TWO MONTHS prior to Baseline examination
• Subjects taking or having taken bisphosphonates of any kind for any reason.
• Female, nonsterile subjects who are pregnant or lactating.
• Subjects who, in the investigator's opinion, would not comply with the study procedures.
• Smokers of any type or former smokers and subjects that take or use any nicotine product.
• Excessive alcohol intake.
• No current restorative or endodontic treatment needs

Where it is running

• University of Colorado — Denver, Colorado, United States

Full record on ClinicalTrials.gov

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