Reduction of IgE Antibody in Human Allergic Subjects

Completed · Phase 1 · Has a placebo group

Conditions studied: Seasonal Allergic Rhinitis

In brief

The purpose of this study is to determine whether a neuropeptide, substance P, when injected along with an allergen, such as ragweed, can reduce allergic reactivity.

Key facts

Study ID

NCT01280149

Run by

Northwestern University

People needed

40

Starts

2011-01-01

Expected to finish

2017-06-20

Last updated by the study team

2018-08-21

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• positive immediate type skin test to ragweed or grass pollen or a third (standardized) allergen if both ragweed and grass pollen allergen are not positive
• volunteers should be available for allergen injections and then cutaneous titrations for approximately 1 year from the start of the enrollment period

You may not qualify if…

• volunteer is pregnant or lactating
• abnormal electrocardiogram for subjects over 50 years of age
• use of beta adrenergic antagonists or tricyclic antidepressants

Where it is running

• Northwestern University Feinberg School of Medicine — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.