Prenatal Cytogenetic Diagnosis by Array-Based Copy Number Analysis

Completed

Conditions studied: Genetic Diseases

In brief

The main objective of the multi-centered collaborative study is to evaluate the accuracy, efficacy and clinical advantages of prenatal diagnosis using microarray analysis as compared with conventional karyotyping.

Key facts

Study ID

NCT01279733

Run by

Columbia University

People needed

4450

Starts

2008-10-01

Expected to finish

2011-10-01

Last updated by the study team

2012-08-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Singleton pregnancy having either chorionic villus sampling in the first trimester or an amniocentesis procedure at or after 16 weeks of gestation performed for prenatal cytogenetic diagnosis
• Karyotyping to be performed at Genzyme Genetics Cytogenetics Laboratory
• Trained study personnel available
• Presenting at pre-specified sites using Genzyme Genetics for routine prenatal diagnostic services

You may not qualify if…

• Unavailability of one or both biologic parents to provide blood sample (e.g. egg or sperm donor, non-paternity)
• Patient refusal to allow follow-up through the neonatal period and up to age two if selected
• Participation in the study in a previous pregnancy
• Insufficient sample for microarray assay

Where it is running

• Columbia University Medical Center — New York, New York, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.