Oscillatory Versus Non-Oscillatory Nasal Continuous Airway Pressure Neonatal Respiratory Support

Withdrawn before enrolling · Not applicable

Conditions studied: Respiratory Distress Syndrome, Prematurity

In brief

This study will seek to enroll neonates requiring Nasal Continuous Airway Pressure (NCPAP) respiratory support and randomize them to either oscillatory (Osc-NCPAP, study group) or non-oscillatory (NCPAP, control group) mode. The goal of the research is to determine if Osc-NCPAP provides improved ventilation support compared to routine NCPAP, i.e. NCPAP without oscillations. This will be measured by need for change to ventilator support, improvement in pCO2 values, and reduction in respiratory rate and frequency of apnea during the period of NCPAP treatment. Other respiratory outcomes will also be compared, including time on NCPAP, time on High-Flow Nasal Cannula support following NCPAP, and time-averaged PiO2 from start of study to end of respiratory treatment.

Key facts

Study ID

NCT01277874

Run by

University of Utah

People needed

0

Starts

2014-12-01

Expected to finish

2017-04-01

Last updated by the study team

2017-03-13

Who can join

Age: any, up to 0. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Newborn (0-28 days of age) admitted to Neonatal Intensive Care Unit (NICU)
• Ordered respiratory treatment of NCPAP

You may not qualify if…

• Major congenital defect
• Known or suspected chromosomal disorder

Where it is running

• Valley Children's Healthcare — Madera, California, United States
• Primary Children's Medical Center — Salt Lake City, Utah, United States
• University of Utah Health Sciences Center — Salt Lake City, Utah, United States

Full record on ClinicalTrials.gov

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