Evaluation of Anti-Inflammatory Treatment in Dry Eye Patients

Completed · Phase 2 · Has a placebo group

Conditions studied: Dry Eye Disease

In brief

The purpose of this study was to determine if difluprednate ophthalmic emulsion is effective in reducing the ocular symptoms of dry eye disease, as measured by a global Visual Analog Scale (VAS) discomfort score.

Key facts

Study ID

NCT01276223

Run by

Alcon Research

People needed

722

Starts

2011-02-01

Expected to finish

2012-01-01

Last updated by the study team

2013-03-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Normal subjects:
• No known history of dry eye disease.
• Non-contact lens wearer.
• No current use of artificial tears or any other dry eye treatment.
• OR
• Dry eye patients:
• At least a 6 month history of dry eye.
• Non-contact lens wearer.
• Uses artificial tears.
• Experiences persistent ocular discomfort.
• Other protocol-defined inclusion criteria may apply.

You may not qualify if…

• The presence of any acute infectious or non-infectious ocular conditions in either eye within 1 month of Visit 1.
• Severe Sjogren's Syndrome.
• Lid function abnormalities.
• Use of steroids, tetracycline, doxycycline, etc., within 30 days of Visit 1.
• History of corneal surgery including refractive surgeries.
• History of glaucoma or ocular hypertension
• Other protocol-defined exclusion criteria may apply.

Where it is running

• Contact Alcon Call Center at 1-888-451-3937 for Trial Locations — Fort Worth, Texas, United States

Full record on ClinicalTrials.gov

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