Efficacy and Safety Study of Low-Dose Ondansetron For Adjunctive Therapy In Adult Patients With Obsessive-Compulsive Disorder
Stopped early · Phase 2 · Has a placebo group
Conditions studied: Obsessive-compulsive Disorder
In brief
This study is to assess the efficacy and safety of two doses of ondansetron (0.5 mg and 0.75 mg) relative to placebo when administered twice daily as adjunctive therapy for adult patients with Obsessive-Compulsive Disorder (OCD) who have not adequately responded to treatment with a serotonin reuptake inhibitor (SRI).
Key facts
- Study ID
- NCT01275248
- Run by
- Transcept Pharmaceuticals
- People needed
- 130
- Starts
- 2011-01-01
- Expected to finish
- 2015-09-01
- Last updated by the study team
- 2013-01-18
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Southwestern Research, Inc. — Beverly Hills, California, United States
- Sun Valley Research Center — Imperial, California, United States
- Pacific Institute for Medical Research — Los Angeles, California, United States
- Compass Research, LLC — Orlando, Florida, United States
- University of South Florida — St. Petersburg, Florida, United States
- Emory University — Atlanta, Georgia, United States
- Carman Research — Smyrna, Georgia, United States
- McLean Hospital — Belmont, Massachusetts, United States
- Beacon Clinical Research, LLC — New Bedford, Massachusetts, United States
- Ambulatory Research Center, Dept of Psychiatry — Minneapolis, Minnesota, United States
- Comprehensive Clinical Research — Berlin, New Jersey, United States
- Biobehavioral Institute, Hofstra — Great Neck, New York, United States
- Eastside Comprehensive Medical Center, LLC — New York, New York, United States
- Columbia University Medical Center NYS Psychiatric Institute — New York, New York, United States
- Montefiore Medical Center, Child Psychiatry Annex — The Bronx, New York, United States
- Richard H. Weisler, MD, PA, and Associates — Raleigh, North Carolina, United States
- Quest Therapeutics of Avon Lake — Avon Lake, Ohio, United States
- Lindner Center of HOPE University of Cincinnati — Mason, Ohio, United States
- The Body Dysmorphic Disorder (BDD) Program — Providence, Rhode Island, United States
- Clinical Trials of Texas, Inc — San Antonio, Texas, United States
- Dean Foundation — Middleton, Wisconsin, United States
- The Rogers Center for Research and Training — Milwaukee, Wisconsin, United States
- Grupo de Estudios Medicos y Familiares — Mexico City, Federal District, Mexico
- Instituto Mexicano de Investigacion Clinica S.A. de C.V. (IMIC) — Mexico City, Federal District, Mexico
- Hospital Aranda de la Parra S.A. de C.V. — León, Guanajuato, Mexico
Full record on ClinicalTrials.gov
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