Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma
Completed · Phase 1
Conditions studied: Brain and Central Nervous System Tumors, Lymphoma, Lymphoproliferative Disorder, Small Intestine Cancer, Unspecified Childhood Solid Tumor, Protocol Specific
In brief
RATIONALE: Imetelstat sodium may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase I clinical trial is studying the side effects and best dose of imetelstat sodium in treating young patients with refractory or recurrent solid tumors or lymphoma.
Key facts
- Study ID
- NCT01273090
- Run by
- Children's Oncology Group
- People needed
- 34
- Starts
- 2011-05-01
- Expected to finish
- 2013-10-01
- Last updated by the study team
- 2014-01-30
Who can join
Age: 1 and older, up to 21. Sex: any. Healthy volunteers: not accepted.
Where it is running
- UAB Comprehensive Cancer Center — Birmingham, Alabama, United States
- Children's Hospital of Orange County — Orange, California, United States
- UCSF Helen Diller Family Comprehensive Cancer Center — San Francisco, California, United States
- Children's National Medical Center — Washington D.C., District of Columbia, United States
- AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus — Atlanta, Georgia, United States
- Children's Memorial Hospital - Chicago — Chicago, Illinois, United States
- Riley's Children Cancer Center at Riley Hospital for Children — Indianapolis, Indiana, United States
- Warren Grant Magnuson Clinical Center - NCI Clinical Trials Referral Office — Bethesda, Maryland, United States
- Dana-Farber/Harvard Cancer Center at Dana-Farber Cancer Institute — Boston, Massachusetts, United States
- C.S. Mott Children's Hospital at University of Michigan Medical Center — Ann Arbor, Michigan, United States
- Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis — St Louis, Missouri, United States
- Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center — New York, New York, United States
- Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States
- Knight Cancer Institute at Oregon Health and Science University — Portland, Oregon, United States
- Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States
- Children's Hospital of Pittsburgh of UPMC — Pittsburgh, Pennsylvania, United States
- St. Jude Children's Research Hospital — Memphis, Tennessee, United States
- Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas — Dallas, Texas, United States
- Baylor University Medical Center - Houston — Houston, Texas, United States
- Children's Hospital and Regional Medical Center - Seattle — Seattle, Washington, United States
- Midwest Children's Cancer Center at Children's Hospital of Wisconsin — Milwaukee, Wisconsin, United States
- Hospital for Sick Children — Toronto, Ontario, Canada
- Hopital Sainte Justine — Montreal, Quebec, Canada
Full record on ClinicalTrials.gov
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