Measurement and Analysis of Macular Retinal Pigment Epithelium (RPE) Elevations With Cirrus HD-OCT vs. Color Fundus Photography

Completed

Conditions studied: Drusen Stage Macular Degeneration

In brief

The objective of this study is to compare the areas designated as elevated retinal pigment epithelium (RPE) by the Cirrus HD-OCT versus those designated as drusen on color fundus photographs (CFPs).

Key facts

Study ID

NCT01272063

Run by

Carl Zeiss Meditec, Inc.

People needed

91

Starts

2010-11-01

Expected to finish

2011-02-01

Last updated by the study team

2013-06-25

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Males or females 50 years of age or older diagnosed to have dry AMD with macular drusen.
• Drusen should not be combined with other lesions such as geographic atrophy (GA) or choroidal neovascularization.
• Able and willing to make the required study visits.
• Able and willing to give consent and follow study instructions.

You may not qualify if…

• History of retinal surgery, laser photocoagulation, and/or radiation therapy to the eye.
• Evidence of other retinal diseases of the eye, including wet AMD, diabetic retinopathy, diabetic macular edema, or significant vitreomacular traction upon dilated examination, or upon evaluation of retinal photos.
• Thick media opacity or inability to fixate that precludes obtaining acceptable scans.
• Concomitant use of hydrochloroquine and chloroquine.
• Unable to make the required study visits.
• Unable to give consent or follow study instructions.

Where it is running

• East Bay Retina — Oakland, California, United States
• West Coast Retina — San Francisco, California, United States
• Bascom Palmer Eye Institute — Miami, Florida, United States
• TLC Eyecare and Laser Centers — Lansing, Michigan, United States

Full record on ClinicalTrials.gov

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