Changes in Endothelial Function and Biomarkers in African Americans (AA) With Metabolic Syndrome

Status unconfirmed · Phase 4

Conditions studied: Hypertension

In brief

The purpose of the study is to compare the effects of Azor (a combination of amlodipine and olmesartan) with Hyzaar ( a combination of losartan and hydrochlorothiazide) on the thin lining on the inside of blood vessels. These cells help keep blood vessels healthy and blood pressure normal.

Key facts

Study ID

NCT01271374

Run by

InVasc Therapeutics, Inc.

People needed

80

Starts

2010-04-01

Expected to finish

2011-12-01

Last updated by the study team

2011-05-05

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• African American
• Hypertension and one of the following:
• Fasting glucose > 100 mg/dl
• HgA1C> 6.0 %
• Plasma triglycerides >150
• HDL cholesterol < 40 mg/dl in men or < 50 mg/dl in women

You may not qualify if…

• History of Heart failure
• use of insulin
• non-dominant arm circ > 50 cm.

Where it is running

• Atlanta Clinical Research Center — Tucker, Georgia, United States

Full record on ClinicalTrials.gov

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