Gene x Behavior Interaction in the Look AHEAD Study

Completed

Conditions studied: Obesity, Type 2 Diabetes

In brief

The interplay of genetic and behavioral factors is critical to understanding obesity. Behavioral weight loss intervention has emerged as a key strategy in combating obesity. However, individuals differ in their degree of success in these programs and genetic factors are known to play a role. In this application, the investigators propose to identify specific genes that predict individual differences in weight loss and high density lipoprotein cholesterol in response to behavioral intervention to help identify individuals that struggle with weight loss and cholesterol despite behavioral efforts.

Key facts

Study ID

NCT01270763

Run by

The Miriam Hospital

People needed

4108

Starts

2009-07-01

Expected to finish

2015-03-01

Last updated by the study team

2015-03-18

Who can join

Age: 45 and older, up to 74. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Enrollment in the Look AHEAD Study, genetic consent

Where it is running

• The Miriam Hospital — Providence, Rhode Island, United States

Full record on ClinicalTrials.gov

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