Efficacy and Safety Study of Leukocyte Interleukin,Injection (LI) to Treat Cancer of the Oral Cavity
Completed · Phase 3
Conditions studied: Squamous Cell Carcinoma of the Oral Cavity, Squamous Cell Carcinoma of the Soft Palate
In brief
The purpose of this study was to determine whether LI administered in combination with cyclophosphamide, indomethacin and zinc in a multivitamin (CIZ) combination prior to standard of care therapy (surgery followed by radiotherapy or concurrent radiochemotherapy) is safe and will increase the overall survival of subjects with previously untreated locally advanced primary squamous cell carcinoma of the oral cavity or soft palate at a median of 3 to 5 years
Key facts
- Study ID
- NCT01265849
- Run by
- CEL-SCI Corporation
- People needed
- 928
- Starts
- 2010-12-01
- Expected to finish
- 2020-12-04
- Last updated by the study team
- 2022-08-19
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Henry Ford Health System Henry Ford Hospital — Detroit, Michigan, United States
- University of Cincinnati Medical Center — Cincinnati, Ohio, United States
- Medical College Of South Carolina MSC550 — Charleston, South Carolina, United States
- VA Puget Sound Healthcare System & University of WA — Seattle, Washington, United States
- HNO-Klinik der medizinischen Universitat Graz — Graz, Austria
- N.N. Alexandrov Research Istitute of Oncology and Medical Radiology — Lyasny, Minsk Oblast, Belarus
- Vitebsk Regional Oncology Dispensary — Vitebsk, Belarus
- University Clinical Centre Tuzla — Trnovac, Tuzla, Bosnia and Herzegovina
- Clinical Center Banja Luka — Banja Luka, Bosnia and Herzegovina
- University Clinical Hospital Mostar — Mostar, Bosnia and Herzegovina
- Clinical Centre University of Sarejevo Clinic for ENT — Sarajevo, Bosnia and Herzegovina
- St. Josephs Healthcare Department of Surgery — Hamilton, Ontario, Canada
- Centre Hospitalier Universitaire de Sherbrooke — Sherbrooke, Quebec, Canada
- CHU de Quebec - L'Hotel Dieu de Quebec — Québec, Canada
- CHC Osijek — Osijek, Croatia
- General Hospital Dr. Josip Bencevic — Slavonski Brod, Croatia
- CH Dubrava — Zagreb, Croatia
- Clinical Hospital Center Zagreb Kispaticeva 12 — Zagreb, Croatia
- KBC Sestre Milosrdnice — Zagreb, Croatia
- KBC Zagreb — Zagreb, Croatia
- ICL 6 avenue Bourgogne CS30519 — Vandœuvre-lès-Nancy, France
- University of Debrecen Medical and Health Scioence Centre — Debrecen, Hajdú-Bihar, Hungary
- National institute of Oncology — Budapest, Rath Gyorgy, Hungary
- Semmelweis University — Budapest, Hungary
- Simmons Cancer Institute at Southern Illinois University — Springfield, Illinois, United States
Full record on ClinicalTrials.gov
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