Cardiometabolic Risk of Shiftwork

Stopped early

Conditions studied: Sleep Deprivation, Circadian Dysregulation, Shift-Work Sleep Disorder

In brief

The overall goal of the present application is to test the hypothesis that shift workers, who are chronically exposed to circadian misalignment and sleep loss, have a higher cardio-metabolic risk than day workers, and that the accumulated sleep debt and the degree of circadian misalignment both predict their elevated cardio-metabolic risk.

Key facts

Study ID

NCT01264913

Run by

University of Chicago

People needed

64

Starts

2009-08-01

Expected to finish

2015-03-01

Last updated by the study team

2016-10-03

Who can join

Age: 18 and older, up to 50. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Day workers and shift workers at the University of Chicago, University of Chicago Medical Center, or another Chicago area medical center who have maintained their work schedule (at least 30 hours/week) for at least 6 months.
• Individuals who have been shift workers for less than 10 years; body mass index <40 kg/m2;
• No major illness
• No history of psychiatric, endocrine, cardiac or sleep disorders
• Those with hypertension or dyslipidemia will be included if these conditions are controlled by a stable treatment.
• Women taking oral contraceptive or hormonal replacement therapy will be included only if they plan to stay on a stable regimen throughout the study.
• Age must be between 18 and 50 years

You may not qualify if…

• Individuals who have worked at the University of Chicago, University of Chicago Medical Center, or another Chicago area medical center in their current position for less than 6 months.
• Individuals who have been shift workers for more than 10 years
• BMI>40 kg/m2
• Individuals with a major illness (e.g. diabetes, sleep disorder)

Where it is running

• The University of Chicago — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.