Post-op Treatment With Hyaluronic Acid Injections

Stopped early · Not applicable

Conditions studied: Meniscus Tear, Chondropathy/Degenerative Joint Disease (DJD)

In brief

This study will look at patients with post-operative treatment of a meniscal tear or degenerative joint disease (degenerative arthritis). They will be randomized into one of three groups: Euflexxa injection, saline (placebo) injection, or no injection. Those who are randomized into the injection group will receive a series of three injections (one a week for 3 weeks), then a "booster" injection at 6 months post-op. Several questionnaires will be given after the first set of injections, then again at a one year follow-up. The hypothesis is that patients receiving hyaluronic acid injections will have better pain and function scores as compared with placebo and no further treatment at all time points.

Key facts

Study ID

NCT01256788

Run by

The Hawkins Foundation

People needed

34

Starts

2010-09-01

Expected to finish

2014-04-01

Last updated by the study team

2019-01-08

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients in post-op stage of treatment for meniscal tears or chondropathy/DJD
• Over 40 years of age
• A daily knee pain above 20mm on a 100mm visual analogue scale

You may not qualify if…

• Previous recipient of viscosupplementation injections
• Had rheumatoid arthritis or other inflammatory arthritis
• Had intra-articular steroid injections within the previous 2 months
• Invasive knee procedures within the past 6 months
• Contraindications to hyaluronate (an allergy)
• Medications that could interfere with the planned interventions

Where it is running

• Steadman Hawkins Clinic of the Carolinas — Greenville, South Carolina, United States

Full record on ClinicalTrials.gov

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