Medical Therapy Versus Sinus Surgery for Chronic Rhinosinusitis: A Prospective, Multi-institutional Study
Completed
Conditions studied: Chronic Rhinosinusitis, Sinusitis
In brief
This investigation is a prospective, multi-institutional cohort study comparing the differences in health-related quality-of-life (HRQoL) improvements between subjects electing continued medical management for chronic rhinosinusitis and those electing medical management plus surgical intervention. Our hypothesis is 3 fold: 1. That patients electing continued medical management will have less disease severity as measured by CT and baseline HRQoL scores, 2. Patients undergoing medical management plus ESS for chronic rhinosinusitis will experience a larger improvement in health related quality of life (HRQoL)compared to patients electing medical management alone, and 3. Patients undergoing medical management plus ESS for chronic rhinosinusitis will use fewer antibiotics, systemic steroids, and miss fewer days of work/school compared to patients electing medical management alone.
Key facts
- Study ID
- NCT01255566
- Run by
- Oregon Health and Science University
- People needed
- 186
- Starts
- 2009-08-01
- Expected to finish
- 2012-08-01
- Last updated by the study team
- 2013-04-24
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults (>= 18 years old)
- Diagnosed with chronic rhinosinusitis
- Failed medical management to date
- Self-selected either sinus surgery or continued medical therapy as next treatment option
- Able to complete surveys in English
You may not qualify if…
- Unable to complete surveys in English
- Children (< 18 years old)
Where it is running
- Northwestern University — Chicago, Illinois, United States
- University of Pennsylvania — Philadelphia, Pennsylvania, United States
- Medical University of South Carolina — Charleston, South Carolina, United States
Full record on ClinicalTrials.gov
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