Probiotics in Primary Care

Completed · Not applicable · Has a placebo group

Conditions studied: Antibiotic Side Effect

In brief

Antibiotics are lifesaving medicines and generally safe, yet unwanted side effects are common. While destroying illness-causing 'bad' bacteria, antibiotics can upset the protective 'good' bacteria in the body. This research will test if taking a probiotic with prescribed antibiotics will decrease the chance of having bothersome antibiotic-associated side effects.

Key facts

Study ID

NCT01254097

Run by

Milton S. Hershey Medical Center

People needed

51

Starts

2011-03-01

Expected to finish

2014-04-01

Last updated by the study team

2015-09-25

Who can join

Age: 18 and older, up to 79. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• adults 18 - 79 years of age with infection requiring an oral antibiotic.
• Must be able to be contacted via telephone.

You may not qualify if…

• pregnancy,
• breast-feeding,
• those receiving tube feeding,
• those with diarrhea as a current symptom of present illness, and pre-existing illnesses that contribute to diarrhea such as inflammatory bowel disease,
• irritable bowel syndrome, colitis or celiac disease.
• Those undergoing active cancer treatments with chemotherapeutic or radiation therapy,
• immunocompromised persons,
• history of cardiac valvular disease,
• those taking a laxative or stool softener on a daily basis, as well as
• persons treated with an antibiotic in the previous 60 days,
• new antibiotic prescription that exceeds a 10 day course, or regular use of a probiotic within the previous three weeks (including daily ingestion of yogurt).

Where it is running

• M.S. Hershey Medical Center, Dept of Family and Community Medicine — Hershey, Pennsylvania, United States

Full record on ClinicalTrials.gov

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