Comparison of Elective Lymph Node Treatment Versus Clinical Observation in the Absence of Palpable Lymph Nodes for High Risk Skin Squamous Cell Carcinoma (SCC)

Stopped early · Not applicable

Conditions studied: High Risk Cutaneous Squamous Cell Carcinoma

In brief

This study will evaluate if there is a difference in survival between elective treatment of draining lymph nodes vs. clinical nodal observation in patients undergoing Mohs surgery for high risk skin squamous cell carcinoma of the head and neck who have a normal lymph node exam. Each treatment arm is accepted as a current standard of care, and the objective is to compare outcomes between the two arms.

Key facts

Study ID

NCT01252329

Run by

University of Pittsburgh

People needed

29

Starts

2011-04-01

Expected to finish

2014-07-14

Last updated by the study team

2017-10-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may not qualify if…

• Satellite metastases
• Clinically abnormal lymph node exam
• Location other than head or neck
• Exclusively mucosal squamous cell carcinoma
• Previous head and neck radiation
• In situ disease, keratoacanthoma subtypes, metatypical or collision tumors
• Inability of subject to give written informed consent
• Pregnancy

Where it is running

• UPMC Department of Otolaryngology — Pittsburgh, Pennsylvania, United States
• Zitelli & Brodland PC — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.