BRCA Mutations in Latinas

Completed

Conditions studied: Breast Neoplasms

In brief

Background: \- BRCA1 and BRCA2 gene mutations have been linked to a higher risk of developing breast cancer and other cancers, and may be associated with types of breast cancer that are more difficult to treat and more likely to recur. New cancer treatments are being developed specifically to treat individuals who have these gene mutations. However, more information is needed about the prevalence of these mutations in minority populations, including Hispanic/Latino populations. To study these populations, researchers are interested in collecting genetic material (DNA) and medical history information from Hispanic/Latino women who have been diagnosed with breast cancer. Objectives: \- To collect saliva samples and medical and family history information from Hispanic/Latino women with breast cancer. Eligibility: \- Hispanic/Latino women at least 18 years of age who have been diagnosed with breast cancer. Design: * Participants will complete a questionnaire with information about place of birth, languages spoken by parents and grandparents, and information about their breast cancer diagnosis. * Participants will provide a saliva sample (2 to 3 tablespoons) for analysis. * No treatment will be provided as part of this protocol....

Key facts

Study ID
NCT01251900
Run by
National Cancer Institute (NCI)
People needed
266
Starts
2011-07-07
Last updated by the study team
2026-07-28

Who can join

Age: 18 and older, up to 99. Sex: female. Healthy volunteers: not accepted.

You may not qualify if…

Where it is running

Full record on ClinicalTrials.gov

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