Mouse Allergen and Asthma Intervention Trial

Completed · Phase 3

Conditions studied: Asthma, Mouse Allergy, Mouse Allergen Exposure

In brief

The MAAIT is a randomized, controlled trial of a home intervention to reduce mouse allergen exposure in mouse allergic children with asthma and mouse allergen exposure. Participants will be randomized to either the Integrated Pest Management (IPM) Group or the Education Group. The IPM Group will receive professional mouse abatement, education, two HEPA filters, allergen-proof mattress and pillow encasements, and targeted cleaning. The Education Group will receive education about IPM at the beginning of the trial and then after completion of the trial, will receive the IPM intervention. Participants will be followed for 12 months.

Key facts

Study ID

NCT01251224

Run by

Johns Hopkins University

People needed

361

Starts

2010-11-01

Expected to finish

2016-09-01

Last updated by the study team

2017-03-16

Who can join

Age: 6 and older, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• persistent asthma
• exacerbation, previous 12 months
• evidence of mouse sensitization
• high levels of mouse allergen in home
• ages 5-17 years

You may not qualify if…

• intermittent asthma
• no exacerbation in previous 12 months
• not sensitized to mouse
• low or undetectable mouse allergen in home
• other lung disease aside from asthma

Where it is running

• Johns Hopkins — Baltimore, Maryland, United States
• Boston Children's — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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