Exercise for Women With Peripheral Arterial Disease
Completed · Not applicable
Conditions studied: Peripheral Artery Disease, Claudication, Women
In brief
Hypothesis #1. Supervised exercise rehabilitation will result in greater increases in exercise performance, peripheral vascular function, and health-related quality of life than compared to the attention-control group. Hypothesis #2. The change in peripheral vascular function will be predictive of improved exercise performance following the supervised exercise program.
Key facts
- Study ID
- NCT01241747
- Run by
- University of Oklahoma
- People needed
- 33
- Starts
- 2009-07-01
- Expected to finish
- 2016-02-01
- Last updated by the study team
- 2019-03-01
Who can join
Age: 60 and older, up to 100. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- women 60 years of age and older having a positive history of intermittent claudication assessed by the San Diego Claudication Questionnaire
- exercise limited by intermittent claudication during a screening treadmill test using the Gardner protocol
- an ankle/brachial index (ABI) < 0.90 at rest or < 0.73 immediately following the treadmill exercise test
- at least one year past menopause
You may not qualify if…
- absence of PAD (peripheral artery disease)
- asymptomatic PAD (Fontaine stage I)
- rest pain due to PAD (Fontaine stage III)
- tissue loss due to PAD (Fontaine stage IV)
- medical conditions that are contraindicative for exercise according to the American College of Sports Medicine (e.g., acute myocardial infarction, unstable angina, etc.)
- use of medications indicated for the treatment of intermittent claudication (cilostazol and pentoxifylline) initiated within three months prior to investigation)
- cognitive dysfunction (mini-mental state examination score < 24)
- active cancer, renal disease, or liver disease
- a calf skin fold measurement > 50 mm, because of potential interference with the light path of the near-infrared spectroscopy probe from penetrating the subcutaneous tissue
- pulse arterial oxygen saturation of the index finger < 95% because of the potential deleterious effect on calf muscle StO2 from poor pulmonary gas exchange
Where it is running
- Clinical Research Center, Penn State College of Medicine — Hershey, Pennsylvania, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.