Study of Lenalidomide in Combination With RICE With Lenalidomide Maintenance Post-Auto Transplant for DLBCL
Completed · Phase 1/Phase 2
Conditions studied: Diffuse Large B Cell Lymphoma
In brief
The standard of care therapy for DLBCL in the relapsed setting is RICE with the plan for the patient to proceed to transplant. This protocol will add Revlimid to the first 7 days of the RICE therapy and again after transplant as maintenance. To improve over all outcome and survival. Hypothesis is that combining lenalidomide with standard of care (RICE) may increase overall response rate thus increasing the number of patients able to proceed with autologous stem cell transplant. This in turn may translate into improved overall survival and progression free survival.
Key facts
- Study ID
- NCT01241734
- Run by
- Hackensack Meridian Health
- People needed
- 18
- Starts
- 2010-10-01
- Expected to finish
- 2015-09-22
- Last updated by the study team
- 2026-04-08
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- John Theurer Cancer Center at Hackensack University Medical Center — Hackensack, New Jersey, United States
- Duke University Medical Center — Durham, North Carolina, United States
Full record on ClinicalTrials.gov
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