Single Oral Dose of Dexamethasone Versus Five Days of Prednisone in Adult Asthma

Completed · Phase 4 · Has a placebo group

Conditions studied: Asthma, Reactive Airway Disease

In brief

This study seeks to compare the effectiveness of a single dose of oral dexamethasone versus 5 days of oral prednisone in the treatment of mild to moderate asthma exacerbations to prevent relapse with an unscheduled return visit to a health care provider for additional asthma treatment within 14 days. The investigators hypothesize that the two treatments will be equally effective in relapse prevention.

Key facts

Study ID

NCT01241006

Run by

Alameda County Medical Center

People needed

376

Starts

2011-01-01

Expected to finish

2015-05-01

Last updated by the study team

2016-01-07

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18-55yo
• History of asthma
• Requires > 1 albuterol nebulizer
• Valid phone number

You may not qualify if…

• declines participation
• Past allergic reaction to corticosteroids
• Use of Oral steroids in the last 2 weeks
• Pregnant
• History of COPD, pulmonary fibrosis, cystic fibrosis, or other chronic lung disease
• History of HIV
• History of CHF
• History of Diabetes mellitus
• Active chickenpox (varicella) or shingles (herpes zoster)
• Active TB
• Requires admission to the Hospital
• Requires immediate airway intervention

Where it is running

• Alameda County Medical Center — Oakland, California, United States

Full record on ClinicalTrials.gov

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