Biological Response of Trauma Patients to Standard Trauma Resuscitation Therapy

Completed · Not applicable · Has a placebo group

Conditions studied: Hemorrhagic Shock

In brief

Overall aim of this work is to evaluate new methods of resuscitation that can be applied by front-line responders on the battlefield, in civilian life, or which can be used during initial resuscitation in the first fixed facility to which the injured patient is brought.

Key facts

Study ID

NCT01239680

Run by

University of Missouri, Kansas City

People needed

5

Starts

2011-01-01

Expected to finish

2013-12-01

Last updated by the study team

2014-06-17

Who can join

Age: 21 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Blunt or penetrating trauma patients who meet Truman Medical Center criteria for a trauma activation.
• These patients will typically be in shock and have blunt injuries or penetrating trauma.
• Patients must be alert, awake, oriented, and responsive and be English speaking males or females between the ages 21-65.

You may not qualify if…

• traumatic cardiac arrest patients,
• pregnant patients,
• interhospital transfer patients,
• non-English speaking patients,
• patients with suspected or confirmed Human Immunodeficiency Virus (HIV) or AIDs based on clear history,
• prior laboratory tests, or strong clinical suspicion; patients with clinical evidence of impaired mental function;
• patients with continuing hypotension or tachycardia after resuscitation;
• patients with blood alcohol in excess of 80mg/dl;
• signs suggestive of coagulopathy;
• allergy to glutamine;
• liver disease or renal disease.

Where it is running

• Truman Medical Center-Hospital Hill — Kansas City, Missouri, United States
• Univeristy of Missouri-Kansas City — Kansas City, Missouri, United States

Full record on ClinicalTrials.gov

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