Does Valproate Increase Levels of Folate Receptor Autoantibodies in Women?

Completed

Conditions studied: Epilepsy, Psychiatric or Mood Diseases or Conditions

In brief

Women who take folate (folic acid) before getting pregnant can lower the risk of giving birth to infant with certain birth defects. However, some medications may affect the action of folate. The purpose of this study is to compare the effect of two anti-epileptic drugs on how folate works in our body.

Key facts

Study ID

NCT01231646

Run by

Northwell Health

People needed

38

Starts

2010-10-01

Expected to finish

2015-07-01

Last updated by the study team

2015-11-20

Who can join

Age: 18 and older, up to 50. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Women ages 18-50 years inclusive who are taking valproate or lamotrigine for neurologic or psychiatric conditions
• Valproate of lamotrigine must be used as monotherapy at stable doses for 6 weeks prior to the study for the neurologic or psychiatric illness; medications taken for other reasons are not excluded.

You may not qualify if…

• Women with prior exposure to valproate or lamotrigine if they are taking lamotrigine or valproate respectively.

Where it is running

• North Shore Long Island Jewish Health System — Great Neck, New York, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.