A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of the Relationship Between Intraoperative Intravenous Acetaminophen and Postoperative Opioid Avoidance for Ambulatory Surgical Procedures

Withdrawn before enrolling · Phase 4 · Has a placebo group

Conditions studied: Postoperative Pain, Intraoperative and Postoperative Opioid Requirements

In brief

This is a research study to determine if giving acetaminophen intravenously in hte operating room will decrease the number of patients who require additional pain medicine, such as morphine, after surgery in the recovery room.

Key facts

Study ID

NCT01231191

Run by

University of California, San Diego

People needed

0

Last updated by the study team

2012-03-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Undergoing ambulatory surgery under general anesthesia
• Expected postoperative pain to be mild-moderate
• Age 18 years or older
• Have an ASA physical status or 1, 2, or 3

You may not qualify if…

• Anticipated peripheral or neuraxial nerve block
• Any physical, mental or medical conditions which may confound quantifying postoperative pain resulting from surgery
• Current chronic opioid or tramadol use
• History of alcohol or opioid abuse
• Known allergy to the study medications
• Pregnancy
• Any health condition requiring greater than 100 micrograms of fentanyl during anesthesia induction
• Treated with any acetaminophen-containing medication in the previous 8 hours
• Treated with MAO inhibitors within 10 days prior to surgery
• Inability to communicate with the investigators and hospital staff
• Known or impaired liver function

Where it is running

• UCSD Medical Center (Hillcrest and Thornton) — San Diego, California, United States

Full record on ClinicalTrials.gov

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