The Efficacy of Automated Intermittent Boluses for Continuous Femoral Nerve Block: a Prospective, Randomized Comparison to Continuous Infusions
Completed · Not applicable
Conditions studied: Arthroplasty, Replacement, Knee, Nerve Block
In brief
The optimal infusion technique (continuous rate vs. intermittent bolus) for peripheral nerve blocks has not been established. To our knowledge, this is the first study to compare the efficacy of an automated intermittent bolus technique to a continuous rate of infusion of local anesthetic in femoral nerve catheters. We hypothesized that the intermittent bolus technique would provide enhanced analgesia compared to a continuous infusion rate as assessed by intravenous patient-controlled analgesia (IV-PCA) hydromorphone consumption and visual analog scale (VAS) pain scores.
Key facts
- Study ID
- NCT01226927
- Run by
- Medical University of South Carolina
- People needed
- 45
- Starts
- 2009-04-01
- Expected to finish
- 2010-04-01
- Last updated by the study team
- 2010-10-22
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- American Society of Anesthesiologists (ASA) physical status 1 through 3
- elective, primary, unilateral TKA
You may not qualify if…
- patient refusal
- pregnancy
- diabetic neuropathy or any other neurologic or neuromuscular disease
- rheumatoid arthritis
- current coagulopathy
- skin infection at needle insertion site for the femoral or sciatic blocks
- significant renal or hepatic impairment
- unsuccessful femoral or sciatic block or femoral catheter placement
- femoral catheter dislodgement after placement
- inability to understand VAS pain scales
- inability to use an IV-PCA pump
Where it is running
- Medical University of South Carolina — Charleston, South Carolina, United States
Full record on ClinicalTrials.gov
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