Statin/Vitamin D & Migraine Study

Completed · Phase 2 · Has a placebo group

Conditions studied: Migraine

In brief

The investigators are studying if taking simvastatin and vitamin D together will help prevent episodic migraines. Simvastatin is an FDA approved drug that is typically used to treat high cholesterol and reduce the risk of stroke and heart attack. Vitamin D is a vitamin found in certain foods like some types of fish, and in nutritional supplements. This study is 9 months long. Some people who participate will receive simvastatin and vitamin D, and some people will receive a placebo. A placebo is a "sugar pill" that looks like medication but does not have any active ingredients in it. The investigators hypothesize that taking vitamin D and simvastatin daily may reduce the number of migraines people who have episodic migraine get.

Key facts

Study ID

NCT01225263

Run by

Rami Burstein

People needed

89

Starts

2010-09-01

Expected to finish

2015-01-01

Last updated by the study team

2016-01-26

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 years or older
• Have had migraines for at least 3 years
• Have between 4 and 15 migraines a month
• Able to speak and read the English language

You may not qualify if…

• Women who are pregnant or nursing, or planning on becoming pregnant in the next 10 months
• Individuals who have a had a heart attack, stroke, peripheral artery disease, atherosclerotic aortic disease, carotid artery disease, or diabetes
• individuals at high risk for cardiovascular disease

Where it is running

• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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