Evaluation of the Impact of Vitrification on Oocytes

Completed · Not applicable

Conditions studied: Fertilization

In brief

The purpose of this study is to determine the rate of cryosurvival of mature oocytes following vitrification, and to then compare the reproductive potential of vitrified oocytes relative to those which have not been cryopreserved.

Key facts

Study ID: NCT01223118
Run by: Reproductive Medicine Associates of New Jersey
People needed: 120
Starts: 2010-08-01
Expected to finish: 2012-07-01
Last updated by the study team: 2013-01-23

Who can join

Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may qualify if…

No prior failed IVF treatment cycle
Female partner less than 35 years of age at time of onset of the IVF cycle
Normal maximum prior day 3 follicle stimulating hormone (FSH) level (< or = 10 IU/L)
Total basal antral follicle count greater than or equal to 12
Male partner with greater than 100,000 total motile spermatozoa Donor sperm is acceptable but the couples will be required to provide one additional vial for DNA analysis
Body Mass Index (BMI) ≤ 32 kg/m2

You may not qualify if…

Diagnosis of chronic oligoovulation or anovulation (cycle typically occurring less often than every 38 days)
Diagnosis of endometrial insufficiency
Clinical indication for PGD (undergoing IVF with PGD to rule out a known genetic defect)
Use of testicular aspiration or biopsy procedures to obtain sperm
Unevaluated ovarian mass
Presence of hydrosalpinges which communicate with the endometrial cavity
Any contraindication to undergoing in vitro fertilization or gonadotropin stimulation

Where it is running

Reproductive Medicine Associates of New Jersey — Morristown, New Jersey, United States
Reproductive Medicine Assoicates of PA at Lehigh Valley — Allentown, Pennsylvania, United States

Full record on ClinicalTrials.gov

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