Use of r-hLH (Luveris) in Donors Previously Treated With r-hFSH (Gonal F)

Completed · Not applicable

Conditions studied: Outcome During r-hFSH Stimulation, Outcome During r-hFSH and r-hLH Stimulation

In brief

The purpose of the study is to compare the safety and efficacy of r-hLH to r-hFSH in the late follicular phase of young women undergoing controlled ovarian stimulation for oocyte donation.

Key facts

Study ID

NCT01223079

Run by

Reproductive Medicine Associates of New Jersey

People needed

20

Starts

2005-12-01

Expected to finish

2008-12-01

Last updated by the study team

2013-03-05

Who can join

Age: 21 and older, up to 32. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Age less than or equal to 32 years old
• BMI<35
• Eligible for controlled ovarian simulation
• No PCO-type ovaries (PCO by USS image, >2.1 LH;FSH ratio on cycle day 3, insulin resistance, increase of testosterone over free testosterone)
• Meet all requirements for becoming an egg donor
• Willingness and ability to participate and comply with study protocol for the duration of the study
• Baseline FSH<11

You may not qualify if…

• Clinically significant systemic disease
• Any contraindication to gonadotropin therapy
• LH:FSH ratio greater than 3
• Pregnancy in the past 3 months
• Any medical condition which, in the judgment of the investigator may interfere with the absorption, distribution, metabolism or excretion of the drug
• Simultaneous participation in another clinical trial
• Known active substance abuse, including tobacco and alcohol (>10 cigarettes/day)
• Refusal or inability to comply with protocol
• Known poor ovarian response

Where it is running

• Reproductive Medicine Assoicates of New Jersey — Morristown, New Jersey, United States

Full record on ClinicalTrials.gov

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