Impact of Vitamin D Therapies on Chronic Kidney Disease

Completed · Not applicable

Conditions studied: Chronic Kidney Disease (CKD), End-stage Renal Disease (ESRD)

In brief

This investigation will consist of a prospective study utilizing two separate populations of patients with 25(OH)D deficiency, one population with chronic kidney disease (CKD) and one with normal renal function.

Key facts

Study ID

NCT01222234

Run by

University of Kansas Medical Center

People needed

56

Starts

2010-10-01

Expected to finish

2012-08-01

Last updated by the study team

2016-05-16

Who can join

Age: 21 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Chronic kidney disease w/GFR<35ml/min
• Nutritional vitamin D deficiency, defined as 25(OH)D < 25ng/ml
• Secondary hyperparathyroidism, PTH>75pg/mL

You may not qualify if…

• Active infection
• Recent hospitalization for acute illness (within last month)
• Refusal to study participation
• History of chronic inflammatory disease process (i.e. inflammatory bowel, rheumatoid arthritis, SLE, etc.)
• Allergy to cholecalciferol or calcitriol
• History of parathyroidectomy
• Functional renal transplant within 5 years
• Current treatment with immunosuppressant medications
• Noncompliance with prescribed medications

Where it is running

• University Of Kansas Medical Center — Kansas City, Kansas, United States

Full record on ClinicalTrials.gov

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