Treatment of Depression in Mothers in Home Visitation

Completed · Not applicable

Conditions studied: Depressive Disorder in Mothers

In brief

This study develops and contrasts In-Home Cognitive Behavioral Therapy (IH-CBT), an adapted evidence-based treatment for depressed mothers participating in home visitation, with typical home visitation in which treatment may be obtained in the community. Mothers will be identified using a two step process consisting of administration of a screen and subsequent diagnosis of Major Depressive Disorder. The will then be randomized into the treatment and control conditions. A comprehensive assessment of depression and related areas of functioning will be administered at pre-treatment, post-treatment, and 3 month follow-up. It is hypothesized that IH-CBT will lead to broad and durable gains in mood and social support relative to those in typical home visitation.

Key facts

Study ID

NCT01221701

Run by

Children's Hospital Medical Center, Cincinnati

People needed

93

Starts

2006-10-01

Expected to finish

2013-02-01

Last updated by the study team

2013-03-18

Who can join

Age: 16 and older, up to 45. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• first-time mother participating in home visitation program
• enrolled in home visitation program for at least 2 months
• 16 years of age or older
• score of 12 or higher on Edinburgh Perinatal Depression Screen at 3 months postpartum
• diagnosis of Major Depressive Disorder using the Structured Clinical Interview for the Diagnostic and Statistical Manual for Mental Disorders
• English speaking

You may not qualify if…

• lifetime history of bipolar disorder, schizophrenia, mental retardation, organic brain syndrome, antisocial personality disorder
• history of psychosis
• current substance dependence
• current antidepressant use or other mood altering medications and/or current involvement in psychotherapy

Where it is running

• Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

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