Computerized Intervention for Amelioration of Cognitive Late Effects Among Childhood Cancer Survivors

Completed · Not applicable

Conditions studied: Brain Tumor, Acute Lymphoblastic Leukemia

In brief

Children treated for a brain tumor (BT) or acute lymphoblastic leukemia (ALL) show elevated rates of working memory impairment. Working memory (WM) is the ability to hold and manipulate information online; for example, when an individual mentally rehearses a phone number in order to dial it without writing it down. A computer-based working memory intervention has been successful in children diagnosed with ADHD and stroke survivors. Individuals participating in the intervention showed improvements on working memory measures as well as more complex problem solving skills. Neuroimaging (brain scans) conducted before and after training showed changes in brain activation suggestive of underlying changes in brain systems that support working memory. This study investigates the effectiveness of this computer-based working memory intervention for childhood cancer survivors.

Key facts

Study ID
NCT01217996
Run by
St. Jude Children's Research Hospital
People needed
128
Starts
2010-10-01
Expected to finish
2013-11-01
Last updated by the study team
2014-04-29

Who can join

Age: 8 and older, up to 16. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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