Study of the Inhibition of [11C]R-rolipram Binding to Brain Phosphodiesterase - 4 (PDE-4) by HT-0712

Stopped early · Phase 1

Conditions studied: Healthy Elderly Volunteers

In brief

This Positron Emission Tomography (PET) imaging study is designed to explore the relationship between HT-0712 dose level and inhibition of brain phosphodiesterase-4 activity, in order to optimize the dosage regimens utilized in subsequent trials.

Key facts

Study ID

NCT01215552

Run by

Dart NeuroScience, LLC

People needed

3

Starts

2010-09-01

Expected to finish

2011-01-01

Last updated by the study team

2011-06-01

Who can join

Age: 55 and older, up to 80. Sex: any. Healthy volunteers: accepted.

Where it is running

• Brookhaven National Laboratory — Upton, New York, United States

Full record on ClinicalTrials.gov

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