Smoking Abstinence and Lapse Effects in Smokers With Schizophrenia and Controls

Completed · Phase 2

Conditions studied: Tobacco Use Disorder, Schizophrenia

In brief

This project tests two hypotheses concerning the low smoking cessation rates in smokers with schizophrenia. The first hypothesis is that smokers with schizophrenia experience stronger and more sustained effects of smoking abstinence on negative mood and smoking urge than control smokers without psychiatric illness. The second hypothesis is that smokers with schizophrenia experience stronger reinforcing effects of a smoking lapse (i.e., more rewarding effects of smoking after a period of abstinence) than control smokers without psychiatric illness.

Key facts

Study ID

NCT01214005

Run by

Brown University

People needed

60

Starts

2009-06-01

Expected to finish

2012-02-01

Last updated by the study team

2012-04-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• cigarette smokers, 20-50 cigarettes per day
• schizophrenia or no psychiatric illness
• age 18 or older
• male or female

You may not qualify if…

• unstable symptoms or medication
• not interested in quitting smoking within 6 months

Where it is running

• Brown University, 121 South Main Street — Providence, Rhode Island, United States

Full record on ClinicalTrials.gov

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