Effect of Whole Body Periodic Acceleration on Airway Endothelial Function
Completed · Not applicable · Has a placebo group
Conditions studied: Healthy, Smokers, Asthma
In brief
In the present proposal the investigators wish to assess the effect of a single session with the device known as Exer-Rest® which applies Whole Body Periodic Acceleration (WBPA) on baseline airway blood flow (Qaw) and in Qaw variation, in current smokers, glucocorticoid-naïve asthmatics, and age-matched healthy never-smokers, with the expectation that the treatment will transiently increase the Qaw, and to a greater extent in the current smokers and patients with asthma who have endothelial dysfunction.
Key facts
- Study ID
- NCT01213706
- Run by
- University of Miami
- People needed
- 45
- Starts
- 2009-10-01
- Expected to finish
- 2011-05-01
- Last updated by the study team
- 2016-08-10
Who can join
Age: 20 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- 15 healthy never-smokers, 15 smokers (> than 1 year smoke history) and 15 never-smokers asthmatics; FEV1 > 80% (except for asthmatics subjets)
You may not qualify if…
- Women of childbearing potential who do not accepted birth control measures; pregnant and breast feeding; cardiovascular disease or use of cardiovascular drugs; respiratory infection during the 4 weeks preceding the study; use of inhaled or systemic glucocorticoids, leukotriene modifiers or theophyllines in asthmatics; FEV1 < 80% on the screening day (excepted for asthmatics subjets)
Where it is running
- Pulmonary Human Research Laboratory, University of Miami Miller School of Medicine — Miami, Florida, United States
Full record on ClinicalTrials.gov
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