Nicotine and Sensorimotor Replacement for Smoking in Smokers With Schizophrenia

Completed · Phase 2 · Has a placebo group

Conditions studied: Tobacco Use Disorder, Schizophrenia

In brief

The objective of this study is to investigate the relative contributions of nicotine replacement and sensorimotor replacement (i.e., smoking denicotinized cigarettes) on abstinence-induced smoking urges, withdrawal-related negative affect, psychiatric symptoms, cognitive task performance and 90-min ad libitum usual-brand smoking behavior in smokers with schizophrenia and non-psychiatric smokers.

Key facts

Study ID

NCT01213524

Run by

Brown University

People needed

75

Starts

2005-09-01

Expected to finish

2011-03-01

Last updated by the study team

2020-10-19

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• schizophrenia or no psychiatric illness
• 18 and older
• men and women
• cigarette smokers, 20-50 cigarettes per day
• would like to quit someday

You may not qualify if…

• medical conditions excluding transdermal nicotine replacement
• pregnancy or lactation

Where it is running

• Brown University, 121 South Main Street — Providence, Rhode Island, United States

Full record on ClinicalTrials.gov

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