Effects of Mental Stimulation in Patients With Mild Cognitive Impairment

Completed · Phase 2

Conditions studied: Mild Cognitive Impairment (MCI)

In brief

The purpose of this study is to learn if activities that challenge the brain (mentally stimulating activities) can improve memory and other types of thinking in patients with Mild Cognitive Impairment. The study will compare the effects of different methods of mental stimulation.

Key facts

Study ID

NCT01212692

Run by

Johns Hopkins University

People needed

63

Starts

2010-10-01

Expected to finish

2014-06-01

Last updated by the study team

2015-12-09

Who can join

Age: 50 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ≥ 50 years of age
• meet criteria for amnestic-Mild Cognitive Impairment (MCI)
• have capacity to give informed consent
• have capacity to complete assessment measures

You may not qualify if…

• history of drug or alcohol dependence
• severe psychiatric conditions associated with psychosis (e.g., schizophrenia)
• recent stroke
• clinical diagnosis of probable Alzheimer's Disease
• history of seizure disorder, serious head trauma, or other medical, psychiatric, or neurological conditions associated with significant cognitive impairment (e.g., Parkinson's Disease, Korsakoff's, HIV)
• current use of Alzheimer's Disease medications (e.g., cholinesterase inhibitors, memantine)

Where it is running

• BPRU, Johns Hopkins Bayview Medical Center — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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