Impact of Glistenings in AcrySof Intraocular Lenses on Visual Quality

Completed

Conditions studied: Lenses, Intraocular, Glistenings, Visual Quality

In brief

This study will assess the impact of IOL glistenings on visual quality and function in patients implanted with a single-piece AcrySof intraocular lens (IOL) that exhibits glistening formations. The primary objective is to determine if random light scattering (measured by C-Quant)correlates with severity of glistenings, other objective measures of visual function (visual acuity, low contrast visual acuity, low contrast visual acuity with glare), and subjective measures of patients' perceptions of their visual quality after cataract surgery (quality of life survey, reports of symptomology and satisfaction).

Key facts

Study ID

NCT01202981

Run by

University of Utah

People needed

200

Starts

2010-07-01

Expected to finish

2013-06-01

Last updated by the study team

2014-12-11

Who can join

Age: any. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Presence of obvious glistenings by slit lamp exam
• Best spectacle corrected visual acuity of 20/20 or better on the Snellen chart at most recent exam

You may not qualify if…

• Any central corneal pathology that could have impact on vision other than mild guttata felt unlikely to have any impact on corneal clarity.
• Any documented glaucoma of any kind.
• Any macular pathology except minimal drusen without retinal pigment epithelial pathology felt to be consistent with normal vision.
• Any diabetic retinopathy other than minimal background diabetic retinopathy felt unlikely to affect vision.
• Any other cause of central visual acuity loss including optic nerve, occipital cortex dysfunction or amblyopia.
• Diagnosis of dry eye syndrome, defined as any corneal staining with fluorescein
• Presence of any central posterior capsular opacification. Previous YAG laser capsulotomy is allowed.
• Any surgical complication having to do with the capsule such as a broken capsule or zonular dialysis or iris trauma or any other complication felt to in any way impact upon the quality of the visual result.
• Any contraindication to pupil dilation

Where it is running

• University of Utah, John Moran Eye Center — Salt Lake City, Utah, United States

Full record on ClinicalTrials.gov

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