Effects of Exercise in People With Tetraplegia
Completed · Not applicable · Has a placebo group
Conditions studied: Spinal Cord Injury, Tetraplegia
In brief
This study is designed to assess the impact of exercise and supplementation on measures of fitness, function, and cardiovascular disease risk factors/modifiers in individuals with spinal cord injury (SCI). The primary purpose of this study is to improve fitness and function, reduce cardiovascular disease risks, and enhance oxidation of dietary and body fats in persons with chronic tetraplegia through acute exercise, exercise conditioning, and dietary supplementation. This study will test the hypothesis that timing of supplementation with regards to exercise bout ('intervention/placebo') affects fitness, function, lipid profiles, lipid oxidation, and inflammatory markers after acute exercise and chronic conditioning.
Key facts
- Study ID
- NCT01202019
- Run by
- University of Miami
- People needed
- 18
- Starts
- 2008-03-01
- Expected to finish
- 2011-09-01
- Last updated by the study team
- 2014-07-22
Who can join
Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- SCI resulting in tetraplegia at C5-C8
- injury for more than one year
- American Spinal Injury Association Impairment Scale (AIS) grade A-C injuries
You may not qualify if…
- Surgery within 6 months;
- pressure ulcer within 3 months;
- upper limb pain that limits completion of exercise;
- recurrent acute infection or illness requiring hospitalization or IV antibiotics;
- pregnancy;
- previous myocardial infarction or cardiac surgery;
- history of glucose-lowering and lipid-lowering drug therapy;
- Type I or II diabetes (by World Health Organization criteria). The following medications and drug therapies will disqualify subjects from participating in the study: beta-adrenergic antagonists, maintenance alpha-adrenergic blockers, Methyldopa, thiazide and loop diuretics, parasympatholytic agents, zinc, estrogen/hormone replacement therapy excluding oral contraceptives, insulin-sensitizing drugs, aspirin, and non-steroidal anti-inflammatory drugs.
Where it is running
- The Miami Project to Cure Paralysis — Miami, Florida, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.