Racial and Genetic Biomarkers of Response in Tissue Samples From Patients With Endometrial Cancer

Completed

Conditions studied: Stage I Uterine Corpus Cancer, Stage II Uterine Corpus Cancer, Stage III Uterine Corpus Cancer, Stage IV Uterine Corpus Cancer

In brief

This research study is studying racial and genetic biomarkers of response in tissue samples from patients with endometrial cancer. Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. DNA analysis of tumor tissue may also help doctors predict how well patients will respond to treatment.

Key facts

Study ID

NCT01198171

Run by

Gynecologic Oncology Group

People needed

243

Starts

2010-01-01

Expected to finish

2017-02-01

Last updated by the study team

2024-08-14

Who can join

Age: any. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Histologically confirmed endometrial cancer
• Stage I-IV disease regardless of grade
• Underwent surgical staging including hysterectomy, bilateral oophorectomy, washings, and pelvic lymphadenectomy
• Eligible and evaluated on GOG-0210 clinical trial, a Molecular Staging Study in Endometrial Cancer
• Available frozen or formalin-fixed and paraffin-embedded normal tissue that is free of tumor cells and yields sufficient high-quality normal DNA for testing
• Consented their specimens and clinical data to be collected and used in future studies
• Self-declared African-American or Caucasian race

Where it is running

• Gynecologic Oncology Group — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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