Clinical Use of Parental Support To Detect Single Gene Mutations
Completed
Conditions studied: Single Gene Disorders
In brief
Gene Security Network has developed a novel technology called Parental Support (PS) which is used for Preimplantation Genetic Screening/Diagnosis (PGS/D) during in vitro fertilization (IVF). This technology allows IVF physicians to identify embryos, prior to transfer to the uterus, which have the best chance of developing into healthy children.
Key facts
- Study ID
- NCT01197872
- Run by
- Natera, Inc.
- People needed
- 240
- Starts
- 2010-09-01
- Expected to finish
- 2013-06-01
- Last updated by the study team
- 2013-07-16
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- At risk couple (mother and father) who are:
- Able to provide laboratory report from commercial CLIA certified laboratory in the United States or legitimate non-US laboratory confirming presence of disease associated mutation in mother and/or father
- Planning to go through IVF and desiring PGD for the specified mutation
- Planning to pursue Chorionic Villus Sampling (CVS) or Amniocentesis if pregnancy occurs and willing/able to provide CVS/ Amniocentesis sample to GSN for confirmatory testing or provide test results of confirmatory testing performed by an external laboratory.
You may not qualify if…
- Couples without prior documentation of genetic mutation as specified above
- Couples where the male partner is not willing, able, or available to provide a semen sample
- Unwilling to have CVS/ Amniocentesis
- In certain cases, unavailability of child sample or other suitable family member: Subjects will not be able to enroll in the study if, in the judgment of the research staff, validation is first required on a child (offspring of male and female subject) and there is no child or other family member that is a suitable substitute available for testing.
Where it is running
- Gene Security Network — Redwood City, California, United States
Full record on ClinicalTrials.gov
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