A Study to Identify Differences in Gene Expression in Patients With Bicuspid and Tricuspid Valve Disease

Completed

Conditions studied: Aortic Valve Disease

In brief

For this study, blood and tissue samples will be collected in order to perform genetic testing to help researchers gather information about this disease and how and why it affects some patients more than others.

Key facts

Study ID

NCT01194362

Run by

Baylor Research Institute

People needed

91

Starts

2010-06-20

Expected to finish

2022-09-23

Last updated by the study team

2026-01-26

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients > or = to 18 years of age
• Presenting with aortic stenosis and to undergo elective aortic valve replacement or repair with or without aortic aneurysm dilation repair
• Able to sign informed consent document

You may not qualify if…

• Patients unable to provide informed consent for any reason
• Patients with predominant aortic regurgitation valve disease
• Patients with other known connective tissue disorders (such as Marfan's Syndrome, Ehlers-Danlos Syndrome)

Where it is running

• The Heart Hospital Baylor Plano — Plano, Texas, United States

Full record on ClinicalTrials.gov

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