Use of 48 Hour Course of Antibiotics to Prevent Surgical Site Infection in Obese Patients Undergoing Cesarean Delivery

Status unconfirmed · Not applicable · Has a placebo group

Conditions studied: Surgical Site Infection in Obese Women Undergoing C-section

In brief

The purpose of this study is to evaluate if preoperative antibiotics, followed by 48 hour course of broad spectrum antibiotics prevents wound infection complications in patients that are obese who undergo cesarean section. Standard antibiotic prophylaxis in all weight women undergoing cesarean section is cefazolin prior to skin incision. It is the hypothesis that a prolonged, 48 hour course of broad spectrum antibiotics that are suited to prevent growth of normal vaginal flora will decrease the rate of surgical site infection in obese patients that are at a greatly increased risk of postoperative infections complications.

Key facts

Study ID

NCT01194115

Run by

University of Cincinnati

People needed

475

Starts

2010-09-01

Last updated by the study team

2011-11-11

Who can join

Age: 13 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• BMI > 30kg/m*2
• Delivery via cesarean section
• consent to participate
• age 13 or older

You may not qualify if…

• known immunodeficiency syndromes
• non-English speaking
• known allergy to cephalosporins or metronidazole

Where it is running

• The Univeristy Hospital — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

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