Laser Based Focal Ablation of Low Grade Prostate Cancer

Completed · Not applicable

Conditions studied: Low Grade Prostate Cancer

In brief

The purpose of this study is to evaluate the safety of MRI-guided laser-induced thermal therapy of biopsy confirmed low-risk prostate cancer.

Key facts

Study ID

NCT01192438

Run by

University of Chicago

People needed

9

Starts

2010-01-01

Expected to finish

2011-09-01

Last updated by the study team

2014-03-27

Who can join

Age: 45 and older. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Male, 45 years of age or older
• Diagnosis of prostate adenocarcinoma
• Clinical stage T1c or T2a
• Gleason score of 7 or less
• A minimum of 12 biopsy cores sampled during diagnostic biopsy
• Three or fewer biopsy cores with prostate cancer
• No single biopsy core with greater than 50% of tumor involvement
• A radiographically visible prostate lesion on MRI with concordance to biopsy sextant
• A documented Karnofsky performance status of at least 70
• Estimated survival of 20 years or greater, as determined by treating physician
• Ability to give informed consent

You may not qualify if…

• Previous surgery, radiation, or androgen deprivation therapy for prostate cancer
• Presence of any condition (e.g., metal implant, shrapnel) not compatible with MRI
• History of previous pelvic radiation
• Severe lower urinary tract symptoms as measured by an International Prostate Symptom Score (IPSS) of 20 or greater. (See Appendix A)
• History of other primary non-skin malignancy within previous three years

Where it is running

• University of Chicago — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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