Investigational Study of Oral Fish Oil in Treating Parenteral Nutrition Associated Liver Disease

Withdrawn before enrolling · Phase 1/Phase 2 · Has a placebo group

Conditions studied: Liver Disease, Short Bowel Syndrome

In brief

The purpose of this study is to investigate the usefulness of oral fish oil(Lovaza)in normalizing liver function in patients who have parenteral nutrition associated liver disease. The investigators believe that patients who take oral fish oil will normalize liver function faster than those who do not

Key facts

Study ID

NCT01191177

Run by

Boston Children's Hospital

People needed

0

Starts

2011-01-01

Expected to finish

2012-01-01

Last updated by the study team

2017-06-22

Who can join

Age: 0 and older, up to 21. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• History of parenteral nutrition(PN)administration >4weeks
• PN associated liver disease from intestinal failure
• ability to take full enteral feed
• body weight equal or greater than 3kg
• elevated ALT level twice of that normal(ALT>84)at the time PN is weaned off

You may not qualify if…

• Hemodynamic instability
• renal failure
• suspected congenital obstruction of the hepatobiliary system
• diagnosis hepatitis A, B, or C
• diagnosis of alpha 1-antitrypsin deficiency
• diagnosis of cytomegalovirus infection
• diagnosis of HIV
• children in care

Where it is running

• Children's Hospital Boston — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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