Monitoring Exhaled Propofol to Individualize General Anesthesia

Completed · Phase 1

Conditions studied: General Anesthesia

In brief

This trial investigates the relationship between concentrations of the anesthetic drug propofol in exhaled breath, blood and drug effect in volunteers undergoing general anesthesia. The main goal of this study is to develop a pharmacokinetic - and dynamic model for propofol in exhaled breath.

Key facts

Study ID

NCT01191021

Run by

University of California, San Francisco

People needed

20

Starts

2010-08-01

Expected to finish

2010-10-01

Last updated by the study team

2013-06-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 18 years of age
• Written informed consent
• Ability and willingness to give written informed consent
• American Society of Anesthesiologists (ASA) risk score I

You may not qualify if…

• Volunteers ASA physical status II - III
• Pregnancy
• Volunteers with history of neurological disease or stroke
• Volunteers with a history of recreational drug abuse
• Volunteers with a history of alcohol abuse
• Smokers
• Anesthesia within 6 months
• Known drug allergies
• History of adverse events during general anesthesia

Where it is running

• Department of Anesthesia and Perioperative Care, UCSF — San Francisco, California, United States

Full record on ClinicalTrials.gov

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