DNA Biomarkers in Tissue Samples From Patients With Osteosarcoma

Completed

Conditions studied: Localized Osteosarcoma, Metastatic Osteosarcoma, Recurrent Osteosarcoma

In brief

This research study is studying DNA biomarkers in tissue samples from patients with osteosarcoma. Studying samples of tumor tissue and blood from patients with cancer in the laboratory may help doctors learn more about changes the occur in DNA and identify biomarkers related to cancer. DNA analysis of tumor tissue may also help doctors predict how well patients will respond to treatment.

Key facts

Study ID

NCT01190943

Run by

Children's Oncology Group

People needed

125

Starts

2010-08-06

Last updated by the study team

2022-03-28

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of osteosarcoma
• Fresh-frozen samples collected at the time of diagnosis with matchedblood DNA (preferred) from patients enrolled on the following osteosarcoma biology protocols:
• COG-P9851
• COG-AOST06B1
• Available clinical outcome data
• Not specified
• Not specified

Where it is running

• Childrens Oncology Group — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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