Grape Seed Extract and Postprandial Oxidation and Inflammation
Completed · Not applicable · Has a placebo group
Conditions studied: Metabolic Syndrome
In brief
The purpose of this study is to determine whether taking grape seed extract prior to eating a high fat meal will reduce the inflammatory response in people with the metabolic syndrome.
Key facts
- Study ID
- NCT01190358
- Run by
- University of California, Davis
- People needed
- 12
- Starts
- 2010-08-01
- Expected to finish
- 2015-09-01
- Last updated by the study team
- 2017-07-19
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- The metabolic syndrome will be diagnosed on the basis of having a combination of any 3 of the following factors:
- Waist circumference of ≥ 40 inches (men) or ≥ 35 inches (women)
- Elevated triglycerides ≥150mg/dl
- HDL cholesterol of < 40mg/dl (men) or < 50mg/dl (women)
- Elevated blood pressure of ≥ 130/85mmHg
- Fasting glucose of > 100mg/dL
You may not qualify if…
- Smokers
- Female subjects who are pregnant or lactating
- Subjects taking any medications that would interfere with outcomes of the study i.e. lipid lowering medications, anti-inflammatory drugs (i.e. ibuprofen), dietary supplements
- Subjects with any known allergy or intolerance to foods involved in the study (cantaloupe, egg, dairy, wheat, grape seed extract)
- Subjects who are actively trying to lose weight
- Subjects with unusual dietary habits (i.e. pica, anorexia nervosa, extreme food restriction, binging and/or purging disorders)
- Subjects who are addicted to drugs or alcohol or who are <1 year recovery program
- Subjects who present with significant psychiatric or neurological disturbances as determined by the primary investigator (i.e. uncontrolled bipolar disorder)
- Subjects with documented atherosclerotic disease, inflammatory disease, diabetes mellitus, uncontrolled hypertension (≥ 140/90mmHg), liver and kidney disease as identified by routine blood tests (chemistry panels). These subjects will be referred to their primary care doctor for further care.
Where it is running
- University of California Davis (Academic Surge, Ragle Human Nutrition Research Facility) — Davis, California, United States
- VA Hospital, Mather — Mather, California, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.