Combination Chemotherapy Before or After Surgery in Treating Patients With Colorectal Cancer With Liver Metastases That Could Be Removed By Surgery

Stopped early · Phase 3

Conditions studied: Colorectal Cancer, Metastatic Cancer

In brief

RATIONALE: Drugs used in chemotherapy work in different ways to kill tumor cells or stop them from growing. Giving combination chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving combination chemotherapy after surgery may kill any remaining tumor cells. It is not yet known whether giving combination chemotherapy before and after surgery is more effective than giving combination chemotherapy after surgery. PURPOSE: This randomized phase III trial is studying giving combination chemotherapy before and after surgery to see how well it works compared to giving combination chemotherapy after surgery in treating patients with colorectal cancer with liver metastases that could be removed by surgery.

Key facts

Study ID

NCT01189227

Run by

NSABP Foundation Inc

People needed

9

Starts

2010-08-01

Expected to finish

2011-12-01

Last updated by the study team

2013-05-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• City of Hope Comprehensive Cancer Center — Duarte, California, United States
• Kaiser Permanente - Fremont — Fremont, California, United States
• Kaiser Permanente Medical Center - Hayward — Hayward, California, United States
• Kaiser Permanente Medical Center - Oakland — Oakland, California, United States
• St. Joseph Hospital Regional Cancer Center - Orange — Orange, California, United States
• Kaiser Permanente Medical Center - Redwood City — Redwood City, California, United States
• Kaiser Permanente Medical Center - Richmond — Richmond, California, United States
• Kaiser Permanente Medical Center - Roseville — Roseville, California, United States
• South Sacramento Kaiser-Permanente Medical Center — Sacramento, California, United States
• Kaiser Permanente Medical Center - Sacramento — Sacramento, California, United States
• Kaiser Permanente Medical Office -Vandever Medical Office — San Diego, California, United States
• Kaiser Permanente Medical Center - San Francisco Geary Campus — San Francisco, California, United States
• Kaiser Permanente Medical Center - Santa Teresa — San Jose, California, United States
• Kaiser Foundation Hospital - San Rafael — San Rafael, California, United States
• Kaiser Permanente Medical Center - Santa Clara Kiely Campus — Santa Clara, California, United States
• Kaiser Permanente Medical Center - Santa Rosa — Santa Rosa, California, United States
• Kaiser Permanente Medical Center - South San Francisco — South San Francisco, California, United States
• Kaiser Permanente Medical Facility - Stockton — Stockton, California, United States
• Kaiser Permanente Medical Center - Vacaville — Vacaville, California, United States
• Kaiser Permanente Medical Center - Vallejo — Vallejo, California, United States
• Kaiser Permanente Medical Center - Walnut Creek — Walnut Creek, California, United States
• University of Colorado Cancer Center at UC Health Sciences Center — Aurora, Colorado, United States
• Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center — Hartford, Connecticut, United States
• Manchester Memorial Hospital — Manchester, Connecticut, United States
• Kaiser Permanente - Deer Valley — Antioch, California, United States

Full record on ClinicalTrials.gov

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